Can Horses Have Phenylephrine?

Infusion of phenylephrine at a dosage of 3 micrograms/kg/min for 15 minutes can be used to induce splenic contraction in horses.

Is phenylephrine a vasoconstrictor or vasodilator?

Phenylephrine is a pure vasoconstrictor and is not recommended for empiric use, although niche uses for phenylephrine include (1) difficulty raising mean arterial pressure in the presence of high cardiac output as well as (2) serious tachyarrhythmias induced by norepinephrine (not usually an issue).

What causes Nephrosplenic entrapment in horses?

It is not clear what the direct cause of nephrosplenic entrapment is. It is hypothesized or suspected that it is a result of colonic motility dysfunction or an accumulation of gas, which allows the large colon to move between the spleen and body wall.

Can you use lidocaine on horses?

Lidocaine is a local anaesthetic agent that is widely used in equine medicine. It is also an Association of Racing Commissioners International (ARCI) Class 2 foreign substance that may cause regulators to impose substantial penalties if residues are identified in post race urine samples.

Is phenylephrine an Inotrope?

Phenylephrine. Phenylephrine is a synthetic alpha-adrenergic receptor agonist with virtually no affinity for beta receptors. Therefore, it is a potent vasoconstrictor with essentially no chronotropic or inotropic effects.

Does phenylephrine cause tachycardia?

Compared to norepinephrine, phenylephrine caused a decreased heart rate, an increase in stroke volume (better diastolic filling), and no reduction in cardiac output. This supports using phenylephrine for patients with hypotension and severe tachycardia (e.g. hypotensive atrial fibrillation).

Is wobbler syndrome in horses painful?

A normal horse will not react but a “Wobbler” will withdraw by depressing the spine in a squatting position. This is not a sign of pain but a sign of weakness as a result of nerve damage.

What is horse phenylephrine?

Affected horses can be treated by giving them an intravenous injection of a drug, phenylephrine, that shrinks the spleen and makes it easier for the colon to become dislodged when the horse is then jogged. Another treatment involves rolling the horse while it is under a short-acting intravenous anesthetic.

What is gastrointestinal distress in horses?

Diarrhea, weight loss, abdominal pain, and protein loss are common signs of intestinal disorders in horses. These signs can be caused by many different disorders, including infectious diseases, parasites, inflammation, tumors, reactions to poisons or drugs, stress, changes in diet, and certain types of colic.

Can Vicks be used on horses?

Vicks VapoRub, or one of its generic equivalents, works as well for relieving congestion from equine respiratory infections as it does for human. Rub it liberally on the skin of the nostrils (not in the nostrils), under the jaw and along the upper trachea/wind pipe.

Can chlorhexidine be used on horses?

Durvet Chlorhexidine 2% Solution, 1 Gallon is an antibacterial aqueous cleaning solution to be applied on superficial cuts, abrasions or insect stings. Effective against gram-positive and gram-negative bacteria. For use on horses and dogs, Provides residual effect up to 2 days, Made in the USA.

Can diclofenac be used on horses?

Diclofenac is a prescription non-narcotic, non-steroidal anti-inflammatory drug (NSAID) that controls pain. Diclofenac is used for the control of pain and inflammation associated with osteoarthritis (OA) in hock, knee, fetlock or pastern joints in horses. 2.

Is phenylephrine an ephedrine?

Ephedrine is Not Phenylephrine | NEJM.

Is phenylephrine direct or indirect?

Phenylephrine is a direct-acting sympathomimetic amine chemically related to adrenaline and ephedrine with potent vasoconstrictor property. Phenylephrine is a post-synaptic alpha-adrenergic receptor agonist that causes vasoconstriction, increases systolic/diastolic pressures, reflex bradycardia, and stroke output.

Is phenylephrine an epinephrine?

Phenylephrine is a sympathomimetic drug, which means that it mimics the actions of epinephrine (commonly known as adrenaline) or norepinephrine. Phenylephrine selectively binds to alpha-1 receptors which cause blood vessels to constrict.

Does phenylephrine make you Bradycardic?

Results: Phenylephrine is a pure vasopressor that only has activity at the alpha-adrenergic receptors. Because it does not have any beta agonist properties to support cardiac output, activation of the baroreceptor may result in bradycardia.

Who should not use phenylephrine?

do not take phenylephrine if you are taking a monoamine oxidase (MAO) inhibitor, such as isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and tranylcypromine (Parnate), or if you have stopped taking one of these medications within the past 2 weeks.

Does phenylephrine cause rebound?

Which nasal sprays cause rebound congestion? Nasal sprays containing either oxymetazoline or phenylephrine are the rebound congestion-inducing nasal sprays to use with caution. If a nasal spray contains either of these active ingredients, be sure to use only as directed on the label — three days or less.

Can horses have strokes?

Some injuries to the nervous system can cause damage that is not evident until 24 to 48 hours after the injury occurs. Longterm damage is usually caused by swelling or internal bleeding of the vessels in the brain. Strokes caused by clogged arteries or high blood pressure are rare in animals.

Can horses get staggers?

Grass staggers, also called ‘grass tetany’ is a disorder where horses can exhibit stagger-like symptoms such as lack of coordination, muscle spasms and tremors. Symptoms differentiate from ryegrass staggers in that during an attack of grass staggers horses cannot eat, drink, defecate or urinate.

Why is my horse walking sideways?

The most common neurological causes of the sidewinder gait were compression of the spinal cord by vertebrae (five horses), equine protozoal myeloencephalitis (four horses) and damage to the spinal cord from unknown causes (four horses).