What Causes Imm In Horses?

Equine immune-mediated myositis (IMM) is a disease occurring in Quarter horses and QH-related breeds that typically causes rapid and severe symmetrical wasting of the topline muscles, often following exposure to or vaccination against respiratory infection by Streptococcus equi, the organism responsible for equine “

What causes rapid muscle loss in horses?

Immune-mediated myositis (IMM) is an autoimmune disease that causes rapid onset of muscle atrophy (wasting) along the topline and hindquarters. This can result in the loss of 40% of muscle mass within 48 hours that can persist for months. The disease has been identified in Quarter Horses and related breeds.

How do you test for IMM in horses?

Genetic testing: For Quarter Horse-related breeds, a definitive diagnosis of IMM and MYHM can now be made by genetic testing through Veterinary Genetics Laboratory at the University of California, Davis.

What causes exertional rhabdomyolysis in horses?

Horses of any age or breed can get sporadic exertional rhabdomyolysis. Common causes include overexertion, muscle trauma, nutritional or electrolyte imbalances and extreme fatigue.

What is MYH1 horse?

Myosin-heavy chain myopathy (MYHM) is a muscle disease in Quarter Horses and related breeds that results in two distinct clinical disease presentations, immune-mediated myositis (IMM) and non-exertional rhabdomyolysis. Both presentations involve muscle loss or damage and are linked to the same genetic variant.

What are two common muscle disorders in horses?

Myopathies are diseases that primarily cause damage to muscles. They may be present at birth (congenital) or occur due to nutritional imbalances, injury, or ingestion of a poisonous substance. Myositis is an inflammatory reaction in muscle.

Can muscle atrophy be reversed in horses?

Some techniques she mentioned included deep-heating ultrasound, electroacupuncture, electrical muscle stimulation, resistance training in water (AquaPacer treadmill), and work on hills or sloped treadmills. “We have had excellent results in regenerating atrophied muscles using physical therapy,” she added.

What does N IMM mean in horses?

Immune-mediated myositis
Understanding the Results

What causes equine recurrent uveitis?

Equine recurrent uveitis is hypothesized to be a complex autoimmune disease influenced by both genetic and environmental factors. Appaloosa horses are particularly susceptible to ERU, and in particular to bilateral disease, which suggests that genetics plays a significant role in ERU risk in this breed.

What is IMM test?

This test measures the amount of immunoglobulins in your blood. Immunoglobulins are also called antibodies.

How do you prevent rhabdomyolysis in horses?

Prevention of further episodes of rhabdomyolysis requires a very gradual increase in the amount of daily exercise horses experience. Minimizing stress, providing regular routines and daily exercise are highly beneficial.

What are the signs of rhabdomyolysis in horses?

Excessive sweating, quick, shallow breathing, rapid heart rate, and muscle tremors are also noticed. In extreme cases, horses may be reluctant or refuse to move and may produce discolored urine due to the release of myoglobin from damaged muscle tissue.

What activities cause rhabdomyolysis?

Causes of rhabdomyolysis include: High-intensity exercise: Jumping into an exercise program too fast can lead to rhabdomyolysis when muscles don’t have time to heal after an intense workout. Severe dehydration and overheating: Heat causes faster muscle breakdown.

What is IMM disease?

Equine immune-mediated myositis (IMM) is a disease occurring in Quarter horses and QH-related breeds that typically causes rapid and severe symmetrical wasting of the topline muscles, often following exposure to or vaccination against respiratory infection by Streptococcus equi, the organism responsible for equine “

What is IMM MYHM?

MYHM is an autosomal codominant genetic disorder that occurs in quarter horses and related breeds, and presents as two equine syndromes: non-exertional rhabdomyolysis or immune-mediated myositis (IMM).

Can a horse recover from EHV?

In most cases, horses exposed to EHV-1 will develop a fever and possibly nasal discharge and then go on to recover. However, the neurologic EHM strain has a high mortality rate of 30-50%. Recovery time can vary from several days to more than a year.

What are the 3 main diseases that affect the muscles?

Types of neuromuscular disorders include: Amyotrophic lateral sclerosis (ALS) Charcot-Marie-Tooth disease. Multiple sclerosis.

What does treatment for equine metabolic syndrome consist of?

Equine metabolic syndrome is treated with dietary management in the form of non-structural carbohydrate (NSC) restriction, restriction of total calorie intake, and a reduction (grazing muzzle) or elimination of pasture access.

What are 3 signs that might indicate to you that a horse might be suffering from illness?

Signs of poor health and horses

• change in appetite or drinking habits.
• change in droppings or signs of diarrhoea.
• change in demeanour or behaviour.
• change in weight (either increase or decrease)
• change in coat/foot condition.

Is vitamin E good for horses?

Vitamin E helps keep a horse’s muscles, nerves and all his internal workings functioning smoothly. And if he’s not getting it naturally in a green pasture, then you’ll need to find a way to add it to his diet. Here’s a look at what vitamin E does and what you can do to make sure your horse gets enough—but not too much.

What causes extreme muscle loss?

Muscle atrophy can occur due to malnutrition, age, genetics, a lack of physical activity or certain medical conditions. Disuse (physiologic) atrophy occurs when you don’t use your muscles enough. Neurogenic atrophy occurs due to nerve problems or diseases.