What Is Dmso In Horse Liniment?

Dimethyl sulfoxide (DMSO) is commonly used topically to treat inflammation in horses. A byproduct of paper production, DMSO was originally created as an industrial solvent; it is now approved for veterinary use by the Food and Drug Administration.

Is DMSO harmful to humans?

Some side effects of taking DMSO include skin reactions, dry skin, headache, dizziness, drowsiness, nausea, vomiting, diarrhea, constipation, breathing problems, and allergic reactions. DMSO also causes a garlic-like taste and breath and body odor.

What does DMSO do for horses?

The anti-inflammatory effect of dimethyl sulphoxide is used in the treatment of muscle trauma, tendinitis, laminitis, and arthritis.

Why DMSO is used?

Dimethyl sulfoxide (DMSO) is a chemical solvent that is sometimes used to help reduce inflammation and pain, and may also be beneficial in reducing leakage during chemotherapy treatment. It has been FDA approved to treat only one condition: interstitial cystitis.

What does DMSO stand for in horses?

Dimethyl sulfoxide (DMSO) has anti-inflammatory and antibacterial properties. From: The Equine Manual (Second Edition), 2006.

Is DMSO a carcinogen?

DMSO is not listed as a carcinogen by regulatory authorities and is actually used as a neutral solvent in the Ames mutagenicity tests. DMSO is not a teratogen in mice, rats or rabbits.

What happens if you get DMSO on your skin?

Industrial grade DMSO may contain a number of impurities that can easily be absorbed into the skin with potentially serious health effects. The most frequent side effects from using DMSO on the skin include: Stomach upset. Skin irritation.

Is DMSO harmful to horses?

The diuretic action of DMSO, however, can make it unsafe for horses who are dehydrated or in shock. It can further dehydrate these animals or dangerously lower their blood pressure.

Is DMSO anti-inflammatory?

Dimethyl sulfoxide is anti-inflammatory and may be applied topically to reduce pain and swelling. More. DMSO, or dimethyl sulfoxide, has a long history as a topical anti-inflammatory agent.

Is DMSO good for nerve pain?

Dimethylsulfoxide (DMSO) is readily absorbed through skin, and relieves musculoskeletal pain when applied topically to painful areas. We studied the effects of DMSO on C-type nerve fibers, which mediate pain sensation. DMSO was applied directly to exposed cat sural nerves.

Does DMSO affect the brain?

DMSO-Induced Neuronal Loss in Hippocampal Culture
DMSO at either 0.5% or 1.0% produces a substantial decrease in the number of cultured hippocampal neurons (p<0.05). The loss of neurons is prevented by the addition of KCl.

What does DMSO do in the brain?

DMSO prevents oxidative stress and reduces swelling of the brain to improve its blood supply. Human brains treated with DMSO immediately after a head injury have reduced swelling within as little as five minutes. Clinical trials have shown significantly extended survival rates in patients with TBI treated with DMSO.

Can you put DMSO on horses legs?

“It makes a great sweat for swollen legs because it reduces edema,” says Fleming, who frequently uses DMSO in his work with endurance horses. Liquid DMSO injections may also be used to treat bowed tendons and other injuries of dense tissues that are difficult to reach with other drugs.

Does DMSO cause DNA damage?

The combined use of DMSO on normal cells and radiosensitizers in the area of cancer cells can have a synergistic effect and further increase DNA damage yields and cell killing [35,36,37].

Does DMSO damage the liver?

Dimethyl sulfoxide (DMSO) can protect the liver from injury produced by a variety of hepatotoxicants when administered prior to or concomitant with the toxicants. This protective action has previously been attributed to DMSO-induced inhibition of bioactivation of the compounds to toxic intermediates.

Is DMSO a neurotoxin?

Dimethyl sulfoxide (DMSO) is a polar organic solvent that is used to dissolve neuroprotective or neurotoxic agents in neuroscience research. However, DMSO itself also has pharmacological and pathological effects on the nervous system.

Can I drink DMSO?

DMSO can be taken orally, topically, intravenously, intramuscularly and intervesically (injected into the bladder).

Why is DMSO not FDA approved?

Research from the 1960’s till 1990’s pinpointed a lot of biologically relevant effects of DMSO. It was even actively investigated for medical use, but because of adverse effects especially affecting the eyes, most clinical trials were halted in 1965 by the United States Food and Drug Administration (FDA).

How long does DMSO stay in the body?

DMSO has a calculated half-life of 16 h in blood; the corresponding value for dimethyl sulfone is 38 h. About 3% of oral doses is exhaled as dimethyl sulfide in humans; the percentage appears to be slightly higher in animals. DMSO can persist in serum for more than 2 weeks after a single exposure.

Does DMSO work for muscle pain?

DMSO is used topically to decrease pain and speed the healing of wounds, burns, and muscle and skeletal injuries. DMSO is also used topically to treat painful conditions such as headache, inflammation, osteoarthritis, rheumatoid arthritis, and severe facial pain called tic douloureux.

What can I use instead of DMSO?

The amphiphilic nature of DMSO along with its relatively low toxicity at dilute concentrations make it a challenging solvent to replace. A possible alternative is Cyrene™ (dihydrolevoglucosenone), an aprotic dipolar solvent that is derived from waste biomass.